MANGUES BAFALLUY, RAMON IR
rmangues@santpau.cat
Alamo Vargas, Patricia Virginia CIBERBBN
Alba Castellon, Lorena IR
Carrasco Diaz, Luis Miguel IR
Garcia Leon, Annabel CIBERBBN
Huaca Manchego, Vanessa IR
Mendoza Fernandez, Julian Ignacio CIBERBBN
Miranda Tovar, Eva IR
Navas Jimenez, Luis Carlos IR
Nuñez Amela, Yaiza IR
Rueda Matas, Ariana IR
Seira Oriach, Clara IR
Unzueta Elorza, Ugutz IR
DEVELOPMENT OF AN ANTIMETHTATIC NANOCONJUGATE DIRECTED TO CXCR4+ METASTATIC STEM CELLS (2014 PROD 00055)
Promote technological development, innovation and quality research
This project is cofunded by European Regional Development Fund (ERDF) allocated by the European Union in the frame of the catalan operative Programme 2014-2020 with 49,750.00€
These equipment and services constitute unit 18 of NANBIOSIS, the integrated infrastructure for the production and characterization of nanomaterials, biomaterials and systems in biomedicine, of CIBER-BBN and the Minimal Invasion Surgery Center Jesús Usón, which has been recognized by Spanish Government as Unique Scientific-Technological Infrastructure (ICTS).
MANGUES BAFALLUY, RAMON IR
rmangues@santpau.cat
Alamo Vargas, Patricia Virginia CIBERBBN
Alba Castellon, Lorena IR
Carrasco Diaz, Luis Miguel IR
Garcia Leon, Annabel CIBERBBN
Huaca Manchego, Vanessa IR
Mendoza Fernandez, Julian Ignacio CIBERBBN
Miranda Tovar, Eva IR
Navas Jimenez, Luis Carlos IR
Nuñez Amela, Yaiza IR
Rueda Matas, Ariana IR
Seira Oriach, Clara IR
Unzueta Elorza, Ugutz IR
Álamo P, Pallares A, Céspedes MV, Falgàs A, Serna N, Sánchez-García L, Morris GA, Casanova I, Mangues R, Vazquez E, Villaverde A, Unzueta U. Fluorescent dye labeling changes the biodistribution of cell-targeted nanoparticles. PHARMACEUTICS 2020, 12 (11):1004; doi:10.3390/pharmaceutics12111004, PMID: 33105866.
IF: 6,3210
Cespedes M.V., Cano-Garrido O., Alamo P., Sala R., Gallardo A., Serna N., Falgas A., Volta-Duran E., Casanova I., Sanchez-Chardi A., Lopez-Laguna H., Sanchez-Garcia L., Sanchez J.M., Unzueta U., Vazquez E., Mangues R., Villaverde A. (2020) Engineering Secretory Amyloids for Remote and Highly Selective Destruction of Metastatic Foci. ADV MATER, 32 (7), -.
IF: 30,8490
Falgas A., Pallares V., Unzueta U., Cespedes M.V., Arroyo-Solera I., Moreno M.J., Gallardo A., Mangues M.A., Sierra J., Villaverde A., Vazquez E., Mangues R., Casanova I. (2020) A CXCR4-targeted nanocarrier achieves highly selective tumor uptake in diffuse large B-cell lymphoma mouse models. HAEMATOLOGICA, 105 (3), 741-753.
IF: 9,9410
Falgas A., Pallares V., Serna N., Sanchez-Garcia L., Sierra J., Gallardo A., Alba-Castellon L., Alamo P., Unzueta U., Villaverde A., Vazquez E., Mangues R., Casanova I. (2020) Selective delivery of T22-PE24-H6 to CXCR4+ diffuse large B-cell lymphoma cells leads to wide therapeutic index in a disseminated mouse model. THERANOSTICS, 10 (12), 5169-5180.
IF: 11,5560
Lopez-Laguna H., Cubarsi R., Unzueta U., Mangues R., Vazquez E., Villaverde A. (2020) Endosomal escape of protein nanoparticles engineered through humanized histidine-rich peptides. SCI CHINA MATER, 63 (4), 644-653.
IF: 8,2730
Lopez-Laguna H., Sanchez-Garcia L., Serna N., Volta-Duran E., Sanchez J.M., Sanchez-Chardi A., Unzueta U., Los M., Villaverde A., Vazquez E. (2020) Engineering Protein Nanoparticles Out from Components of the Human Microbiome. SMALL, (), e2001885-.
IF: 13,2810
Lopez-Laguna H., Sanchez J., Unzueta U., Mangues R., Vazquez E., Villaverde A. (2020) Divalent Cations: A Molecular Glue for Protein Materials. TRENDS BIOCHEM SCI, 45 (11), 992-1003.
IF: 13,8070
Montanuy H., Martinez-Barriocanal A., Antonio Casado J., Rovirosa L., Ramirez M.J., Nieto R., Carrascoso-Rubio C., Riera P., Gonzalez A., Lerma E., Lasa A., Carreras-Puigvert J., Helleday T., Bueren J.A., Arango D., Minguillon J., Surralles J. (2020) Gefitinib and Afatinib Show Potential Efficacy for Fanconi Anemia-Related Head and Neck Cancer. CLIN CANCER RES, 26 (12), 3044-3057.
IF: 12,5310
Pallarès V, Unzueta U, Falgàs A, Sánchez-García L, Gallardo A, Morris G, Alba-Castellón L, Álamo P, Serna N, Sierra J, Villaverde A, Vázquez E, Casanova I, Mangues R. An Auristatin nanoconjugate targeting CXCR4+ leukemic cells blocks AML dissemination. J HEMATOL ONCOL 2020 Apr 15;13(1):36. doi: 10.1186/s13045-020-00863-9. PMID: 32295630.
IF: 17,3880
Riera P., Artigas-Baleri A., Salazar J., Sebio A., Virgili A.C., Arranz M.J., Paez D. (2020) ABCB1 Genetic Variants as Predictors of Irinotecan-Induced Severe Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients. FRONT PHARMACOL, 11 (), -.
IF: 5,8100
Sanchez-Garcia L., Sala R., Serna N., Alamo P., Parlade E., Alba-Castellon L., Volta-Duran E., Sanchez-Chardi A., Unzueta U., Vazquez E., Mangues R., Villaverde A. (2020) A refined cocktailing of pro-apoptotic nanoparticles boosts anti-tumor activity. ACTA BIOMATER, 113 (), 584-596.
IF: 8,9470
Serna N., Alamo P., Ramesh P., Vinokurova D., Sanchez-Garcia L., Unzueta U., Gallardo A., Cespedes M.V., Vazquez E., Villaverde A., Mangues R., Medema J.P. (2020) Nanostructured toxins for the selective destruction of drug-resistant human CXCR4+ colorectal cancer stem cells. J CONTROL RELEASE, 320 (), 96-104.
IF: 9,7760
Serna N, Carratalá JV, Parladé E, Sanchez-Chardi A, Avinyó A, Unzueta U, Mangues R, Eritja R, Ferrer-Miralles N, Vázquez E, Villaverde A. Developing protein-antitumoral drug nanoconjugates as bi-functional antimicrobial agents. ACS APPL MATTER & INTERFACES 2020 Dec 30;12(52):57746-57756020 Dec 16. doi:10.1021/acsami.0c18317. Online ahead of print, PMID: 33325705.
IF: 9,2290
Serna N., Cano-Garrido O., Sanchez-Garcia L., Pesarrodona M., Unzueta U., Sanchez-Chardi A., Mangues R., Vazquez E., Villaverde A. (2020) Engineering Protein Venoms as Self-Assembling CXCR4-Targeted Cytotoxic Nanoparticles. PART PART SYST CHAR, 37 (6), -.
IF: 3,3100
Unzueta U., Roldan M., Pesarrodona M., Benitez R., Sanchez-Chardi A., Conchillo-Sole O., Mangues R., Villaverde A., Vazquez E. (2020) Self-assembling as regular nanoparticles dramatically minimizes photobleaching of tumour-targeted GFP. ACTA BIOMATER, 103 (), 272-280.
IF: 8,9470
Vargas-Nadal G., Munoz-Ubeda M., Alamo P., Arnal M.M., Cespedes V., Kober M., Gonzalez E., Ferrer-Tasies L., Vinardell M.P., Mangues R., Veciana J., Ventosa N. (2020) MKC-Quatsomes: a stable nanovesicle platform for bio-imaging and drug-delivery applications. NANOMED-NANOTECHNOL, 24 (), -.
IF: 6,4580
Volta-Duran E., Cano-Garrido O., Serna N., Lopez-Laguna H., Sanchez-Garcia L., Pesarrodona M., Sanchez-Chardi A., Mangues R., Villaverde A., Vazquez E., Unzueta U. (2020) Controlling self-assembling and tumor cell-targeting of protein-only nanoparticles through modular protein engineering. SCI CHINA MATER, 63 (1), 147-156.
IF: 8,2730
