Oncogénesis y fármacos antitumorales

Álamo P, Pallares A, Céspedes MV, Falgàs A, Serna N, Sánchez-García L, Morris GA, Casanova I, Mangues R, Vazquez E, Villaverde A, Unzueta U. Fluorescent dye labeling changes the biodistribution of cell-targeted nanoparticles. PHARMACEUTICS 2020, 12 (11):1004; doi:10.3390/pharmaceutics12111004, PMID: 33105866.

IF: 6,3210

Cespedes M.V., Cano-Garrido O., Alamo P., Sala R., Gallardo A., Serna N., Falgas A., Volta-Duran E., Casanova I., Sanchez-Chardi A., Lopez-Laguna H., Sanchez-Garcia L., Sanchez J.M., Unzueta U., Vazquez E., Mangues R., Villaverde A. (2020) Engineering Secretory Amyloids for Remote and Highly Selective Destruction of Metastatic Foci. ADV MATER, 32 (7), -.

IF: 30,8490

Falgas A., Pallares V., Unzueta U., Cespedes M.V., Arroyo-Solera I., Moreno M.J., Gallardo A., Mangues M.A., Sierra J., Villaverde A., Vazquez E., Mangues R., Casanova I. (2020) A CXCR4-targeted nanocarrier achieves highly selective tumor uptake in diffuse large B-cell lymphoma mouse models. HAEMATOLOGICA, 105 (3), 741-753.

IF: 9,9410

Falgas A., Pallares V., Serna N., Sanchez-Garcia L., Sierra J., Gallardo A., Alba-Castellon L., Alamo P., Unzueta U., Villaverde A., Vazquez E., Mangues R., Casanova I. (2020) Selective delivery of T22-PE24-H6 to CXCR4+ diffuse large B-cell lymphoma cells leads to wide therapeutic index in a disseminated mouse model. THERANOSTICS, 10 (12), 5169-5180.

IF: 11,5560

Lopez-Laguna H., Cubarsi R., Unzueta U., Mangues R., Vazquez E., Villaverde A. (2020) Endosomal escape of protein nanoparticles engineered through humanized histidine-rich peptides. SCI CHINA MATER, 63 (4), 644-653.

IF: 8,2730

Lopez-Laguna H., Sanchez-Garcia L., Serna N., Volta-Duran E., Sanchez J.M., Sanchez-Chardi A., Unzueta U., Los M., Villaverde A., Vazquez E. (2020) Engineering Protein Nanoparticles Out from Components of the Human Microbiome. SMALL, (), e2001885-.

IF: 13,2810

Lopez-Laguna H., Sanchez J., Unzueta U., Mangues R., Vazquez E., Villaverde A. (2020) Divalent Cations: A Molecular Glue for Protein Materials. TRENDS BIOCHEM SCI, 45 (11), 992-1003.

IF: 13,8070

Montanuy H., Martinez-Barriocanal A., Antonio Casado J., Rovirosa L., Ramirez M.J., Nieto R., Carrascoso-Rubio C., Riera P., Gonzalez A., Lerma E., Lasa A., Carreras-Puigvert J., Helleday T., Bueren J.A., Arango D., Minguillon J., Surralles J. (2020) Gefitinib and Afatinib Show Potential Efficacy for Fanconi Anemia-Related Head and Neck Cancer. CLIN CANCER RES, 26 (12), 3044-3057.

IF: 12,5310

Pallarès V, Unzueta U, Falgàs A, Sánchez-García L, Gallardo A, Morris G, Alba-Castellón L, Álamo P, Serna N, Sierra J, Villaverde A, Vázquez E, Casanova I, Mangues R. An Auristatin nanoconjugate targeting CXCR4+ leukemic cells blocks AML dissemination. J HEMATOL ONCOL 2020 Apr 15;13(1):36. doi: 10.1186/s13045-020-00863-9. PMID: 32295630.

IF: 17,3880

Riera P., Artigas-Baleri A., Salazar J., Sebio A., Virgili A.C., Arranz M.J., Paez D. (2020) ABCB1 Genetic Variants as Predictors of Irinotecan-Induced Severe Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients. FRONT PHARMACOL, 11 (), -.

IF: 5,8100

Sanchez-Garcia L., Sala R., Serna N., Alamo P., Parlade E., Alba-Castellon L., Volta-Duran E., Sanchez-Chardi A., Unzueta U., Vazquez E., Mangues R., Villaverde A. (2020) A refined cocktailing of pro-apoptotic nanoparticles boosts anti-tumor activity. ACTA BIOMATER, 113 (), 584-596.

IF: 8,9470

Serna N., Alamo P., Ramesh P., Vinokurova D., Sanchez-Garcia L., Unzueta U., Gallardo A., Cespedes M.V., Vazquez E., Villaverde A., Mangues R., Medema J.P. (2020) Nanostructured toxins for the selective destruction of drug-resistant human CXCR4+ colorectal cancer stem cells. J CONTROL RELEASE, 320 (), 96-104.

IF: 9,7760

Serna N, Carratalá JV, Parladé E, Sanchez-Chardi A, Avinyó A, Unzueta U, Mangues R, Eritja R, Ferrer-Miralles N, Vázquez E, Villaverde A. Developing protein-antitumoral drug nanoconjugates as bi-functional antimicrobial agents. ACS APPL MATTER & INTERFACES 2020 Dec 30;12(52):57746-57756020 Dec 16. doi:10.1021/acsami.0c18317. Online ahead of print, PMID: 33325705.

IF: 9,2290

Serna N., Cano-Garrido O., Sanchez-Garcia L., Pesarrodona M., Unzueta U., Sanchez-Chardi A., Mangues R., Vazquez E., Villaverde A. (2020) Engineering Protein Venoms as Self-Assembling CXCR4-Targeted Cytotoxic Nanoparticles. PART PART SYST CHAR, 37 (6), -.

IF: 3,3100

Unzueta U., Roldan M., Pesarrodona M., Benitez R., Sanchez-Chardi A., Conchillo-Sole O., Mangues R., Villaverde A., Vazquez E. (2020) Self-assembling as regular nanoparticles dramatically minimizes photobleaching of tumour-targeted GFP. ACTA BIOMATER, 103 (), 272-280.

IF: 8,9470

Vargas-Nadal G., Munoz-Ubeda M., Alamo P., Arnal M.M., Cespedes V., Kober M., Gonzalez E., Ferrer-Tasies L., Vinardell M.P., Mangues R., Veciana J., Ventosa N. (2020) MKC-Quatsomes: a stable nanovesicle platform for bio-imaging and drug-delivery applications. NANOMED-NANOTECHNOL, 24 (), -.

IF: 6,4580

Volta-Duran E., Cano-Garrido O., Serna N., Lopez-Laguna H., Sanchez-Garcia L., Pesarrodona M., Sanchez-Chardi A., Mangues R., Villaverde A., Vazquez E., Unzueta U. (2020) Controlling self-assembling and tumor cell-targeting of protein-only nanoparticles through modular protein engineering. SCI CHINA MATER, 63 (1), 147-156.

IF: 8,2730